Friday September 6th

The 6th of Friday was the last day where SENS6 delegates were able to exchange their scientific value before a large audience. Of course,there were a great amount of interesting and unforgettable reports, but I want to share my impressions of the short talk by Anastasia Shindyapina,a promising young scientist (Lomonosov Moscow State University,Russia),who represented a modern views on the regulated process of mineralization in aging soft tissues. It is supposed that mechanisms leading to calcium salts deposition in soft tissues could be a highly regulated process and ways leading to these disorders are also different and depend on patient gender,disease type and age. However calcium apatite accumulation can be find in the different tissue type and also leading to osteoporosis,atherosclerosis and chronic kidney disease. Evidently,researchers have not a clear idea in order to the calcification mechanisms. Nevertheless the scientific interest and awareness of a vital issue associated with longevity were leading to a modern method- bioinformatic analysis of the molecular pathways underlying calcification in atherosclerosis and chronic kidney disease patients, signaling pathways of collagen cross-links formation and bone mineralization and supposed new potential targets to calcification treatments and review drugs for the targets.
It seems to be the first significant step in order to understand age-related mineralization which is going on well and shows a big promise in future agong research.
In addition to the above it is necessary to remind a recent Anastasia Shindyapina and her collegues(Mr. Garik V Mkrtchyan, Miss Tatiana Gneteeva, Mr. Sveatoslav Buiucli, Dr. M Kulka, Dr. B Tancowny, Mr. Alexander Aliper, and Dr. Alexander Zhavoronkov) achievement — published work «Mineralization of the connective tissue: a complex molecular process leading to age-related loss-of-function» in Rejuvenation Research journal(July,2013)


The next exciting and essential age -related issue was reported by Alex Zhavoronkov
(Director and trustee of Biogerontology Research Foundation). The new economic arguments for accelerating aging research were proposed by Alex. Really, economic analysis and inestimable advantage concerning longevity extension should be well improved and mathematically established in order to be sure that long-lived society will not face an economic instability in
long-range guess. So, in addition to the above Alex Zhavoronkov introduced new parameters that can be used to the economic growth models:rate of clinical adoption,biomedical progress rate and the rate of change in retirement age.The biomedical progress rate is comprised of the rejuvenation rate .extending the productive lifespan and the non-rejuvenating rate,extending the life-span after the age at which the net contribution to the economy becomes negative.
Nevertheless the citizen attitude to life extension achievement is very different and it is also depend on our parents and grandparents life experience and views.So,
it is necessary to change our world outlook and believe in the power of healthy living.